Compounded drug notice
Compounded semaglutide is prepared for an individual patient by a U.S. pharmacy licensed in the state where it
dispenses, under a prescription from a licensed provider. Federal law permits compounded drugs to be prescribed,
but they are not FDA-approved, and the FDA does not review them for safety, effectiveness or
manufacturing quality. Compounded semaglutide is not Ozempic® or Wegovy® and is not a generic or
equivalent version of either. CAPO Health is not affiliated with, endorsed by or sponsored by Novo Nordisk A/S;
all trademarks are the property of their respective owners. Prescription required. Not everyone qualifies.
Individual results vary.
Warning: risk of thyroid C-cell tumors
In rodent studies, semaglutide caused thyroid C-cell tumors. It is not known whether semaglutide causes thyroid
C-cell tumors, including medullary thyroid carcinoma (MTC), in people. Do not use semaglutide if
you or a family member has ever had MTC, or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
Tell your provider right away if you notice a lump or swelling in your neck, hoarseness, trouble swallowing or
shortness of breath.
What it is used for
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. When prescribed for weight management it is
used together with a reduced-calorie diet and increased physical activity in adults with obesity, or with
overweight and at least one weight-related medical condition. Whether it is appropriate for you is decided by your
licensed provider after reviewing your health history. It has not been studied in combination with other GLP-1
medicines and is not for people with type 1 diabetes.
Do not use semaglutide if you
- have, or a family member has had, medullary thyroid carcinoma (MTC);
- have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2);
- have had a serious allergic reaction to semaglutide or any of its ingredients;
- are pregnant, planning to become pregnant, or breastfeeding;
- are already taking another GLP-1 receptor agonist medicine.
How it is taken
Once a week, on the same day each week, as a subcutaneous injection under the skin of the abdomen, thigh or upper
arm. Your provider starts at a low dose and increases it gradually according to how you tolerate it. Use a new
needle for every injection and never share vials or needles.
Before starting, tell your provider if you
- have or have had problems with your pancreas (pancreatitis) or kidneys;
- have type 2 diabetes and a history of diabetic retinopathy;
- have or have had gallbladder problems or severe stomach problems such as gastroparesis;
- have a history of depression or suicidal thoughts;
- take insulin, sulfonylureas or any other medicine for diabetes;
- are scheduled for surgery or a procedure under anesthesia or deep sedation;
- take any other prescription or over-the-counter medicines, vitamins or herbal supplements — semaglutide slows
stomach emptying and can change how oral medicines are absorbed.
Pregnancy and breastfeeding
Semaglutide should not be used during pregnancy and may harm an unborn baby. If you plan to become pregnant, stop
semaglutide at least two months beforehand, as it stays in the body for a long time. It is not known
whether semaglutide passes into breast milk; discuss feeding options with your provider.
Serious side effects — get medical help right away
- Inflammation of the pancreas (pancreatitis): severe pain in the stomach area that does not go
away, with or without vomiting, sometimes spreading to the back.
- Gallbladder problems, including gallstones: pain in the upper stomach, fever, yellowing of the
skin or eyes, clay-colored stools.
- Low blood sugar (hypoglycemia), more likely if you also take insulin or a sulfonylurea:
dizziness, sweating, shakiness, confusion, blurred vision, fast heartbeat.
- Kidney problems: vomiting or diarrhea can cause dehydration, which may worsen kidney function.
- Serious allergic reactions: swelling of the face, lips, tongue or throat, trouble breathing or
swallowing, severe rash, rapid heartbeat.
- Changes in vision in people with type 2 diabetes.
- Increased heart rate while at rest.
- Depression or thoughts of suicide — report any change in mood or behavior.
- Food or liquid entering the lungs during surgery or procedures under anesthesia or deep sedation.
Common side effects
Nausea, diarrhea, vomiting, constipation, stomach pain, headache, tiredness, upset stomach, dizziness, bloating,
belching, gas, stomach flu, heartburn and reactions at the injection site. Digestive symptoms are most common when
starting or increasing the dose and often ease over time. This is not a complete list.
This summary does not replace the full prescribing information and is not medical advice. Discuss every risk and
benefit with your licensed provider before starting or changing treatment. If you experience a serious side
effect, contact your provider; in an emergency, call 911. Suspected adverse reactions can also be
reported to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. Individual results vary.